Blood Group from Day 0, Haemoglobin Genotype from age of 6months in most regular laboratories but can also be done in newborns in specialized laboratory.

When their is pain, give more water and fluids, give basic painkillers like paracetamol or ibuprofen but if pain persists despite these simple measures, you have to take the child to the hospital immediately for further treatment usually giving the fluids and analgesic into the veins

Yes it is possible to have a child with positive Rhesus factor.

Haemoglobin Genotype can be checked from the age of 6 months and Blood group from Day 0 in most regular laboratories but can also be done in newborns in specialized laboratory.

It is not advisable because they could produce offsprings with sickle cell disease