You will need Rhogam injection when pregnant as you're O -ve. Your hospital will guide you on that during antenatal care.

Rhesus factor incompatibility might set in pregnancy. For a woman with Rh- negative and her baby is Rh- positive (inherited from the dad), her body will approach the Rh- positive protein as something that's foreign. This means that if blood cells from your baby cross your bloodstream,which can happen during pregnancy, labor, and delivery, your immune system will make antibodies against your baby's red blood cells. If you have an Rh- negative blood type, you’re considered sensitized to your baby once your body has made these antibodies. This means that your body might send these antibodies across the placenta to attack your baby's red blood cells. the effects of Rh incompatibility can be prevented by getting an injection of Rh immuneglobulins (RhIg) during your first trimester or during a miscarriage,or while having any bleeding during your pregnancy. This blood product contains antibodies to the Rh factor. So discuss your Rh factor with your doc as soon as you take in.

What's your husband Genotype? That's what matters the most. If you are AS, it is advisable you marry someone with AA to avoid getting birth to a baby with sickle cell Anaemia.